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If you have a job posting and would like to advertise it here, send your information to office(at)hupo.org and we'll post it for you. The price for each listing is $200 USD (IAB members and all academic positions submitted by a HUPO member are free of charge). Listings are posted for 60 days.

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  • Company
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Current Job Postings

  • 19 Feb 2024 8:16 AM | Anonymous member (Administrator)

    POSITION TITLE: Staff Scientist 1 (Mass Spectrometry-Based Proteomics of Alzheimer’s Disease)
    COMPANY: The National Institutes of Health
    LOCATION: Bethesda, MD

    Summary of Position:

    The National Institute on Aging (NIA), Intramural Research Program (IRP), a major research component of the National Institutes of Health (NIH) in the Department of Health and Human Services (DHHS), is seeking applications from highly motivated individuals to serve as a Staff Scientist in the Center for Alzheimer’s and Related Dementias (CARD) in Bethesda, MD. CARD is a collaborative initiative between the NIA and National Institute of Neurological Disorders and Stroke (NINDS) that supports basic, translational, and clinical research on Alzheimer’s disease and Alzheimer’s disease related dementias (AD/ADRD). CARD’s central mission is to initiate, stimulate, accelerate, and support research that will lead to the development of improved treatments and preventions for these diseases.

    CARD is a highly collaborative research center that aims to be a central hub for collaboration and cooperation. The science performed in CARD is collaborative and team-based in nature and there will be a large number of scientists and research groups working with or at CARD with varied expertise and from around the world. In the initial phase, CARD is focused on understanding biology, anchored in genetics; prediction and prognosis of disease; de-risking targets; and precision therapeutics.

    CARD is seeking to recruit an expert in proteomic technologies, including mass spectrometry and the application of high-multiplex, high-throughput proteomic assays including next generation sequencing based proteomics. The successful candidate must be committed to scientific excellence and highly collaborative research and will foster this throughout the development of a group focused on proteomics. The successful individual must have a Ph.D. or equivalent doctoral degree in Proteomics, Biomedical Sciences, or related fields, with at least 5 years of postdoctoral experience working in a laboratory setting.

    The successful individual will have had productive postdoctoral experience as evidenced by a record of primary and collaborative authorship in peer-reviewed publications in internationally recognized journals. The incumbent will be an expert in the application and/or development of proteomic methods using varied sources to include blood, plasma, brain, cells, and other tissues. Additionally, the incumbent will be an expert in mass spectrometry applied for the discovery and delineation of disease biology and for use in biomarker identification and development. Experience in the generation, quality control, handling, and analysis of large-scale proteomic data is preferred. Experience in neurodegenerative disease research is essential.

    The successful candidate will manage projects and collaborations through project initiation, strategy development, strategic planning, execution, and closeout of phases of projects. The candidate will be responsible for problem-solving and making key decisions to ensure the completion of multiple projects, goals, and competing priorities. A proven track record in establishing and maintaining collaborative relationships is highly desirable. Furthermore, the selected candidate will assist in the management of resources from CARD for funding start-up costs and ongoing program operations, and will be assist with managing budget, personnel, and space relating to proteomics within CARD. The incumbent will have a role in assisting the CARD Director in project prioritization, and in identifying research and development opportunities that fit within the program and mission of CARD.

    Staff Scientists do not receive independent resources, although they often work independently and have sophisticated skills and knowledge essential to the work of the Center. Although this Staff Scientist will be supervised by the CARD Senior Scientist, they will be interacting with the scientists from the IRP and scientific community at large.

    Salary is commensurate with research experience and accomplishments. A full Civil Service package of benefits (including retirement, health and life insurance, Thrift Savings Plan participation, etc.) is available. All employees of the Federal Government are subject to the conflict-of-interest statutes and regulations, including the Standards of Ethical Conduct. Additional information regarding CARD is available at the following website: https://www.nia.nih.gov/research/card

    To apply:
    Please send a cover letter, curriculum vitae, bibliography, statement of research interests, and three letters of recommendation to: Aisha McCoy, Intramural Program Specialist; Office of the Scientific Director, National Institute on Aging; Vacancy #CARD-24-02-AM; via email: cardjobs@mail.nih.gov. Applications, including letters of recommendation, must reference Vacancy #CARD-24-02-AM. The first round of reviews is expected to occur on or about March 21, 2024; however, applications will be accepted until the position is filled.

    DHHS and NIH are Equal Opportunity Employers. The NIH is dedicated to building a diverse community in its training and employment programs and encourages the application and nomination of qualified women, minorities, and individuals with disabilities.

  • 05 Feb 2024 7:28 AM | Anonymous member (Administrator)

    POSITION TITLE: Proteomics Mass Spectrometry Specialist - Research Scientist
    COMPANY: Mayo Clinic in Florida
    LOCATION: Jacksonville, FL, United States

    Summary of Position:
    The Research Scientist must play a key supporting role in the sponsoring research program. Will significantly contribute to grant writing and serve as co-principal investigator (if necessary) on extramural grant applications submitted by the principal investigator. May apply as the co-investigator or co-principal investigator with other investigators or principal investigator for an extramural grant or contracts if done in collaboration with his/her Mayo sponsor. The Research Scientist is expected to serve as the principal investigator's internal and external representative and resource contact person for the research program and may represent the principal investigator at national or international meetings if necessary. Brings a unique skill, technique or knowledge to the program and will significantly participate in personnel and resource management on behalf of the principal investigator. Will independently manage assigned projects and the projects of other program personnel. Will provide input for the direction and design of other's projects and direct teaching activities within the investigator's program. The newly established Multi-Omics Mass Spectrometry Core seeks candidates for a Proteomics Mass Spectrometry Specialist at the level of Research Scientist, with the ability to perform common mass spectrometry related research methods, including sample preparation, instrument method development and implementation, and delivery of data analyses. This enterprise-wide core is located on the Florida campus and will initially provide mass spectrometry-based proteomic services, with plans for future expansion of lipidomic and metabolomic services. It will be the candidate’s responsibility to perform mass spectrometry sample preparation, instrument maintenance and data analysis:

    1) Work with core director on consulting with users to advise on the project design
    2) Perform sample preparation for mass spectrometry analysis, with an initial focus on proteomics.
    3) Maintain core laboratory space, track inventory, and order supplies.
    4) Perform maintenance and method optimization and develop and maintain standard operating procedures and protocols for the core.
    5) Utilize bioinformatics tools to analyze results, distribute data to submitting researchers, and provide help with troubleshooting as necessary.
    6) Work closely with the Director to meet the demands of the core.
    7) Track instrument usage and assist Director in developing reports to OCSS advisory committee and central administration.

    The new Multi-Omics Mass Spectrometry Core will provide Mayo Clinic translational and discovery scientists with access to sophisticated and customizable mass spectrometry-based testing at single cell sensitivity that will facilitate deeper understanding of diseases at the molecular level, will aid in the discovery of new therapeutic targets and biomarkers, and will support development of personalized treatment strategies. The initial emphasis of the core will be on proteomic analyses, but the ultimate goal of the core is to provide mass spectrometry-based platforms for a true multi-omics approach that covers proteomics, metabolomics, and lipidomics.

    Qualifications: 
    A Research Scientist candidate must have a doctoral level degree and a minimum of 6 years of postdoctoral research training at Mayo or elsewhere. Must hold academic rank (i.e. Instructor, Assistant Professor) at Mayo at the time of accepting the Research Scientist position or achieve it immediately thereafter. The candidate must bring a unique skill, technique or knowledge to the sponsoring program as documented by professional accomplishments and publication record and will have made a career decision to pursue regular employment at Mayo in support of an established research staff program. The ideal candidate will have a Ph.D. with current knowledge in mass spectrometry, proteomics, and bioinformatics, and experience performing LC-MS/MS based proteomic analyses (ideally on Bruker timsTOF) and pertinent data analysis software. Additional expertise in spatial and single cell proteomics, as well as other mass spectrometry techniques is a plus. The successful applicant will need to be able to take initiative, and quickly assimilate new techniques and concepts. Good interpersonal skills are important to facilitate interactions with investigators from diverse scientific fields.

    Link to full description:
    https://fa-euwp-saasfaprod1.fa.ocs.oraclecloud.com/hcmUI/CandidateExperience/en/sites/Mayo-US/job/326077

    Contact information:
    In addition to submitting the online application, interested individuals should send a cover letter, full curriculum vitae, and contact information for 2-3 references to Dr. Wilfried Rossoll via e-mail at: rossoll.wilfried@mayo.edu 

  • 05 Feb 2024 7:21 AM | Anonymous member (Administrator)

    POSITION TITLE: PhD or Post doctoral fellow in Translational Cardiac Proteomics
    COMPANY: University of Copenhagen
    LOCATION: Copenhagen, Denmark, Europe

    Summary of Position:
    The Cardiac Proteomics Group at University of Copenhagen seeks to appoint a talented PhD student and a postdoctoral fellow to outline protein regulations involved in the pathogenesis of cardiometabolic syndrome. The research fellows will investigate remodeling in hearts from animal models, patient samples as well as cell systems using quantitative proteomics-based approaches to identify molecular changes driving the disease state. The two fellows will be part of a collaborative research environment and can expect involvement in multiple projects, covering experimental investigations of cellular and animal disease models in addition to work with human samples. We are seeking highly motivated scientists to join our team. Prior experience with mass spectrometry based proteomics is required.

    Qualification Requirements:
    The candidate holds a degree with experience from a relevant field including but not limited to Biotechnology, Biochemistry or Biomedical Sciences. Ambitious, creative, independent and self-driven Hands on skills and expert knowledge in one or more of the following areas: Experimental know-how of mass spectrometry-based proteomics (LC-MS/MS) Analytical know-how of Mass spectrometry data analysis Experimental know-how of various types of sample preparations (such as proteomics, PTMomics, clinical proteomics, spatial- or single cell proteomics, secretomics, interactomics using high-resolution mass spectrometry). Experience in quantitative proteomics approaches Experience in cardiac biology or physiology is an advantage Good communication skills in English, both oral and written, is a requirement Being willing to engage in team work Preferred applicants should have an excellent academic track record, solid research experience and be highly motivated to deploy diverse strategies to extract novel findings of importance to cardiac pathophysiology.

    Our group and environment: 
    The candidates will be part of the Cardiac Proteomics group led by Professor Lundby at the Department of Biomedical Sciences at the University of Copenhagen, Denmark. Successful candidates will be working in a team of scientists across multiple scientific fields focused on improving our molecular understanding of cardiac pathophysiologies. Our facilities include state-of-the-art laboratories and core facilities as well as modern office spaces. The position provides a unique opportunity to develop expertise in cutting edge quantitative mass spectrometry-based proteomics, data analysis of large datasets and integration of multi-omics datasets. Striving for academic excellence, collegial respect and freedom tempered by responsibility, we offer creative, friendly and stimulating working conditions in a dynamic and strong scientific environment.

    View here for full job description and for applying:
    Post doctoral applicants: https://employment.ku.dk/faculty/?show=161046
    PhD applicants: https://employment.ku.dk/phd/?show=160987

    Contact detail: Prof. Alicia Lundby, Cardiac Proteomics Group, Department of Biomedical Sciences, University of Copenhagen.
    Email: alicia.lundby@sund.ku.dk

  • 23 Jan 2024 10:40 AM | Anonymous member (Administrator)

    POSITION TITLE: Post Doctoral Associate in Biological and Translational Proteomics
    COMPANY: Broad Institute of MIT and Harvard
    LOCATION: Cambridge, MA, United States

    Summary of Position:

    The highly interdisciplinary and collaborative proteomics group at the Broad Institute of MIT and Harvard is looking for strongly motivated post-doctoral associates with relevant experience to step into exciting, highly visible and impactful roles in internationally-recognized efforts to 1) develop and apply state-of-the art proteomics technologies to address important and translatable questions in biology and clinical medicine or 2) lead data analysis and interpretation in projects that leverage the vast amount of multiomic and proteogenomic data that is generated by the group.  Successful candidates would have the immediate opportunity to contribute to one of more of the following areas:

    • Drive multiomic and proteogenomic studies in cancer, metabolic disease and neurological disorders to gain biological insights and identify new therapeutic vulnerabilities
    • Deepen understanding of immune biology with implications for enhancing immunotherapy
    • Define the landscape and function of cellular signaling networks modulated by protein phosphorylation, ubiquitylation, acetylation (PTMs) and their cross-talk
    • Elucidate mechanisms of response and resistance to therapy
    • Develop and optimize new, broadly enabling proteomic technologies
    • Employ spatial proteomics methods for understanding heterogeneity
    • Identify candidate diagnostic and predictive markers of disease presence and stage using MS and non-MS based methods 

    Successful candidates will work as part of an interdisciplinary team of clinicians, biologists, computational and proteomics scientists at the Broad and with an international group of renowned partner institutions to deeply characterize and understand the proteomes, PTM-omes and metabolomes of soft tissues, cells and biofluids.

    Candidates must have:

    • An MD or Ph.D. in biology, biochemistry, or a closely related field
    • Excellent scientific productivity, evidenced by high-quality research publications in peer reviewed journals
    • A track record of conducting independent and creative research
    • Excellent verbal and written communication skills

    Practical skills and knowledge are required in one or more of the following areas:

    • State-of-the-art mass spectrometry-based proteomics
    • Statistical and/or computational analysis of large-scale proteomic or genomic data
    • Analysis of cell signaling pathways/networks
    • Cell biology/ biochemical methods to understand protein function
    • Molecular biology/CRISPR-based genome editing

    The Broad Institute is a world-leading non-profit research organization dedicated to realizing the promise of the post-genomic era for human benefit.  Located in Cambridge, MA with strong ties to MIT, Harvard, and world class Boston hospitals, the Broad Institute brings together scientists of diverse backgrounds to solve critical problems in biology and medicine in an interdisciplinary manner. The Broad Institute, and the embedded Proteomics Group (www.broadinstitute.org/proteomics), have an outstanding track-record in training the next generation of research scientists and in developing and applying proteomic technologies critical to address important questions in biology and medicine. We collaborate with top-level researchers throughout the world, and results of these studies and our technology developments are published in top-tier journals.  

    Link to full description:

    https://broadinstitute.wd1.myworkdayjobs.com/en-US/broad_institute/job/Cambridge-MA/Postdoctoral-Associate---Proteomics-Group-Carr-Lab_37946

    Contact information:

    Interested scientists are encouraged to apply on-line at the Broad Website.  Inquiries can also be addressed to Dr. Steven Carr, Sr. Director of Proteomics, Broad Institute (scarr@broad.mit.edu) and Namrata Udeshi, Associate Director of Proteomics (Udeshi@broadinstitute.org) or jobs-proteomics@broadinstitute.org.  

  • 22 Jan 2024 2:38 PM | Anonymous member (Administrator)

    POSITION TITLE: Post-doctoral Fellow
    COMPANY:  The Pirrotte Lab
    LOCATION:  Phoenix, Arizona, USA

    View here for all details. 

    The Pirrotte lab is actively seeking a highly motivated and skilled individual to join our dynamic team as a Post-Doctoral Fellow at the Translational Genomics Research Institute. This position offers a unique opportunity to contribute to the forefront of scientific discovery by developing innovative methods in single-cell proteomics and applying them to translational cancer research. The successful candidate will possess a strong background in mass spectrometry, cell biology, proteomics sample preparation, and advanced quantitative data analysis, with a particular emphasis on interpreting complex results. Bioinformatics expertise is considered a valuable asset.

    Key Responsibilities:

    • Develop and optimize methods for single-cell proteomics.
    • Apply cutting-edge techniques to advance translational research objectives.
    • Conduct proteomics sample preparation and mass spectrometry experiments.
    • Perform data analysis and interpretation of results.
    • Collaborate with multidisciplinary teams to integrate bioinformatics approaches.
    • Disseminate results at conference meetings and author manuscripts.

    If you are passionate about pushing the boundaries of single-cell proteomics, contributing to translational research, and working in a collaborative and innovative environment, we encourage you to apply. Join us at the Translational Genomics Research Institute and be a part of groundbreaking discoveries that shape the future of scientific knowledge.

    Why join TGen?

    TGen is a non-profit research institute located in Phoenix, Arizona. We are focused on translational science – and have been since our formation in 2002. Our immediate goal is to make a difference in the lives of patients suffering from disease. We are moderately sized (~300 employees), nimble, and house the latest technologies in genomics. Do you dream of your work

    benefiting patients sooner rather than later? We have a 20-year track record in doing exactly that. It is the perfect sized place for you to start and grow your career and receive expert mentorship from a diverse, successful group of investigators.

    Moreover, our Post Doctoral Research Fellows enjoy the same benefits as any other employee.

    Our compensation packages are competitive with the NIH, and our benefits are top notch! Just to name a few of the perks of working for us:

    • Health coverage through Blue Cross Blue Shield of Arizona. Mayo Clinic is in network.
    • Dental, Vision, Life, Short- and Long-Term Disability
    • Excellent Enterprise Assistance Program with a full scope of life services
    • 401k with up to a 6% match
    • Generous time off
    • Commuter benefits
    • Much, much more!

    Why come to Phoenix, Arizona?

    Relocation packages are available to move to the beautiful Valley of the Sun! Phoenix is an incredible place to live! Like the outdoors? We average 300 sunny days each year – 100 more sunny days than the typical U.S. city. With an average of only 30 days with rain your recreational plans rarely get ruined. We have multiple mountain ranges within a 30-minute drive of the city center, California or Mexico beaches are a quick five-hour drive away, and, in the winter, snow sports are just a two-hour drive north to Flagstaff. Our airport is consistently ranked as one of the best in the country with direct flights to all major U.S. cities, Europe, and the Americas. Enjoy long weekends in Vegas? Drive there in five hours or fly there in 45 minutes. We also have great nightlife, performing arts, food, college and professional sports, and live music. Arizona is truly one of the nation’s best-kept secrets. Lastly, the scientific community in Phoenix is large and constantly growing – research and clinical partners abound!

    Please include a CV, a personal statement, and at least three references that can be contacted.

    Apply here

  • 12 Jan 2024 6:00 PM | Anonymous member (Administrator)

    POSITION TITLE: Postdoctoral Position in the Functional Cellular Networks Section, Laboratory of Immune System Biology
    COMPANY:  National Institute of Allergy and Infectious Diseases (NIH) 
    LOCATION: Bethesda, MD


    A postdoctoral position is available in the Functional Cellular Networks Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD. The successful candidate would join an interactive team of researchers in a collaborative scientific environment focused on systems immunology approaches to studying the Toll-like receptor, inflammasome and other innate immune signaling pathways.

    For more information and recent publications, please visit: https://www.niaid.nih.gov/research/aleksandra-nita-lazar-phd

    Requirements: Applicants must have (or expect soon) a Ph.D., M.D., or M.D./Ph.D. from an accredited institution obtained less than five years ago, an ability and enthusiasm for independent research, an interest in interdisciplinary approaches and collaborations, and publications in peer reviewed journals. The projects will focus on innate immunity signaling networks and mechanisms, for example, the immune system protein abundance changes, functional interactions and post-translational modifications, ultimately leading to mathematical modeling of the cell signaling driving the innate immune response, as well as specific protein roles in the innate immune signaling.                     

    Demonstrated background in protein biochemistry is essential, knowledge of innate immunity, microbiology, virology and/or mass spectrometry-based proteomics strongly recommended, experience with analysis of post-translational modifications (phosphorylation, glycosylation, ubiquitination) and/or the methods of studying protein-protein interactions (such as microscopy-based methods), and basic techniques of immunology a plus. Salary is commensurate with research experience and accomplishments.

    The NIH is dedicated to building a diverse community in its training and employment programs.

    To Apply: Applicants should send their curriculum vitae, a brief statement of research interests, and the names and contact information of three references to:

    Aleksandra Nita-Lazar, Ph. D., Senior Investigator
    Functional Cellular Networks Section, Laboratory of Immune System Biology
    National Institute of Allergy and Infectious Diseases;
    email: nitalazarau@niaid.nih.gov

  • 11 Jan 2024 4:02 PM | Anonymous member (Administrator)

    POSITION TITLE: Two Year Postdoctoral Position
    COMPANY:  University of Southern Denmark
    LOCATION: Odense, Denmark 

    • Postdoctoral Position Available For Studying The Role Of Sialic Acids In Early Brain Development Using Brain Organoids
    • Application Deadline February 1, 2024

    Job Description:

    Protein glycosylation, the process of attaching sugar units to proteins that reside on the surface of cells, plays a crucial role in cell communication and migration, vital for the formation of organs like the brain. A significant distinction between humans and our primate kin is the existence of a sugar molecule known as sialic acids (SA) on the proteins of cell surfaces. Humans, due to a mutation in the CMAH gene (which converts N-acetylneuraminic acid (Neu5Ac) into N-glycolylneuraminic acid (Neu5Gc)), only possess the precursor molecule Neu5Ac. In contrast, greater Apes possess both Neu5Ac and Neu5Gc. This mutation occurred post our common ancestry with chimpanzees. This alteration in SAs has led to changes in proteins that interact with sialic acid and other related proteins. Coupled with other variations in enzymes associated with SA biology between humans and monkeys, these changes could affect brain development and contribute to unique human traits. In our current project, we aim to utilize gene editing technology (CRISPR/Cas9) to alter key genes involved in SA biology in induced pluripotent stem cells (iPSCs). We will then use these modified cells to investigate early brain development in iPSC-derived 3D brain organoids, employing Omics and imaging techniques. For further information please click the following link:

    Full job description and application process

    CONTACT DETAILS:

    Prof. Martin R. Larsen, Department of Biochemistry and Molecular Biology at the University of Southern Denmark

    E-mail: mrl@bmb.sdu.dk



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