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  • 30 Mar 2021 4:16 PM | Anonymous member (Administrator)

    Sanjeeva Srivastava, IIT Bombay, India

    The flourishing field of advanced multi-omics technologies opened new avenues for understanding health and disease biology, specifically identifying disease-specific biomarkers and developing potential therapies. Among all multi-omics technologies, Proteomics has time and again proved vital to provide insight into disease pathology. The workflow of designing a proteomics experiment and making sense out of that data is always challenging, especially for beginners in the field.

    To aid these scientists and students, Prof. Sanjeeva Srivastava from IIT Bombay, in collaboration with DST, India, organized a two weeks’ workshop on ‘Basics and Advanced Proteomics Approaches Workshop’ from 15th to 26th February 2021 to spread the knowledge in high throughput proteomics technologies and the data analysis strategies using advanced software like- MaxQuant, Proteome Discoverer, MetaboAnalyst and Reactome.

    This event was a success due to the eminent scientists and experts from the industry from India and Abroad who shared their research experience, knowledge, and expertise in that field. In addition to that, Participants, mainly faculties from different universities/ institutions of India, made the workshop more interactive rather than lecture series. All participants were provided some group projects to make them more confident in data analysis and to build collaboration between them in the near future.

    The first week of the workshop was conducted to enlighten the participants’ knowledge in MS-based proteomics, various approaches of quantitative proteomics like- gel-free and gel-based proteomics, and acquaint them with software for primary proteomic data analysis. In the morning sessions, plenary speakers including Prof. Marc Wilkins, Matthias Ulhén, Bernhard Küster, and Prof. Mark Baker, other eminent scientists including Prof. Surekha Zingde, Utpal Tatu, Mathias Wilhelm, Anthony Purcell gave an insightful talk on various aspects of proteomics and its applicability in clinical research. The afternoon sessions were designed to give the participants a hands-on experience in sample preparation for quantitative proteomics, including protein extraction and digestion, sample run in the mass spectrometer, monitoring of sample run, and primary and secondary analysis of proteomics data. The second week of the workshop was designed to introduce participants to the high throughput proteomics technologies like targeted proteomics, label-free biosensors like SPR, BLI, protein microarray, and network analysis to infer the biological significance from the MS data. In this week, participants got the opportunity to hear from esteemed scientists and researchers in the proteomics field Prof. Xiaobo Yu, Prof. Henning Hermjakob, Dr. Jau-song Yu, Dr. Suman Thakur. This week was more enriched with tech-talks; Mr. Michael Johnson, Dr. Rodrigo Barderas, Dr. Tian-Hua Wang, Dr. Debadeep Bhattacharyya shared their research work and the developed techniques to elevate the proteomic research. The major attraction of the second week was the group project which made participants more familiar with handling the mass spectrometric data.

    Nowadays, it has become essential to upgrade us with current trends and advances in proteomics technologies to facilitate the translation of lab research to clinics. Herewith, this two weeks long workshop gave the participants an insight to use these high-throughput proteomics technologies for the progression of the clinical research.

    All the workshop recordings are available at Proteomics Workshop YouTube video playlist link: https://youtube.com/playlist?list=PLIaqGH0Iwt3h01pDpyAvyJe_9PIxE1f2I

  • 25 Mar 2021 4:19 PM | Anonymous member (Administrator)

    The HUPO B/D-HPP Executive Committee is excited to announce an upcoming human proteome webinar organized by B/D-HPP in April/May 2021! The webinar will be the start of a series of online events to highlight recent progresses in proteome research from leading investigators around the globe.

    The theme of the first webinar will be "PTMs in Human Disease". This 3-hour event will feature talks from ~5 to 7 leading experts on proteomics approach toward multiple types of common and rare post-translational modifications in the human proteome. More information including speaker list, title, webinar time and weblink will be posted in the coming weeks. Please stay tuned!

  • 02 Mar 2021 4:44 PM | Anonymous member (Administrator)

    Did you know HUPO has a YouTube channel? From the 2017 world congress welcome address by former 47th Vice President of the United States Joseph R. Biden Jr., to a series of interviews on perspectives in proteomics, check out videos recorded at our past congresses on YouTube.


    An interview series of proteomics experts has been undertaken over the last several HUPO world congresses, and describe the challenges and goals of current basic and clinical research in the proteomics field. This perspective series is directed by Prof. Sanjeeva Srivastava, IIT Bombay, Mumbai.

  • 02 Mar 2021 4:43 PM | Anonymous member (Administrator)

    July 6-8, 2021

    Abstract submission and early bird registration are now open for the British Society for Proteome Research (BSPR) Interact 2021 meeting. The conference features prominent and upcoming scientists from the UK and across the globe, presenting the latest research and methodology in the field of proteomics, as well as participating in round table discussions.

    For more information, including on how to register and submit your abstract, please visit www.bspr-interact.com. To stay up to date, follow the BSPR on Twitter and Facebook @UKBspr, and join the BSPR LinkedIn group @BSPR - British Society for Proteome Research.

  • 02 Mar 2021 4:42 PM | Anonymous member (Administrator)

    Did you attend HUPO Connect? Don't forget you have access to all recordings until March 31, 2021. Didn't attend HUPO Connect? On-demand recordings are still available for purchase. Learn more..

  • 02 Mar 2021 4:42 PM | Anonymous member (Administrator)

    The Nominations and Elections Committee will be seeking candidates to serve on HUPO Council for a three-year term beginning January 2022 (2022-2024). Call for nominations will open on Thursday, March 25, 2021. Stay tuned for more updates in the weeks to come!

  • 02 Mar 2021 4:41 PM | Anonymous member (Administrator)

    Do you know someone who has made an impact in the field of proteomics and deserves recognition for it? Nominate them for a HUPO award. Submission deadline is Friday, April 30, 2021. Click here to review the nomination requirements and submit...

  • 01 Feb 2021 5:20 PM | Anonymous member (Administrator)

    Checkout the latest HUPOST released today: February HUPOST 2021

  • 12 Jan 2021 3:11 PM | Anonymous member (Administrator)

    Stephen Pennington, HUPO Past President, UCD Conway Institute, Ireland

    It has been a genuine privilege and honour to have had the opportunity to serve as HUPO President for the past two years. The COVID-19 global pandemic has made the last 9-10 months very challenging for the HUPO community and leadership team (Executive Committee). Our thoughts go to those in our community who have been directly impacted and especially those who have lost loved ones.

    I’m sure we are all conscious of the devastating negative health and social consequences of COVID-19. Amongst the very many negatives it is reassuring, and perhaps necessary, to hold onto some positive outcomes from the pandemic. The increase in public and professional awareness of the science of biology and virology, of diagnostic testing and vaccine development has been remarkable to witness. Proteomics has been at the front and centre of these efforts. Likewise, the importance of global collaboration and sharing of data has been in the spotlight. This is something that isn’t new to HUPO as global collaboration and data sharing has been at the heart of HUPO and its various initiatives for many years. We should all be proud of the contribution proteomics has made and continues to make to all aspects of COVID-19 research and clinical practice. It behoves us all to publicise these efforts and capitalise the increased public awareness and support for biological sciences to more generally promote the importance of the very real global impact of proteomics research. Raising the profile of proteomics and its “success stories” has been a consistent priority for the HPP and we should now be poised to progress this with renewed vigour.

    HUPO is a global organisation that promotes equality and diversity. The dramatic events of 2020 highlighted the importance of making all aware of this. I am very grateful to Sue Weintraub not only for her steadfast support as Vice-President but also for carefully crafting HUPO’s diversity statement.

    The HUPO Congresses are a highlight of the HUPO year and they have continued to showcase the very best of proteomics, presented by the very best of proteomics researchers at all stages of their scientific experience. In 2019, we had the opportunity to participate in a wonderful congress in Adelaide, Australia. Organising such a successful Congress takes a huge amount of effort so without naming names I’d like to thank the local organisers for hosting the superb science, the HPP day and allied events such as the ICPC and Immuno-peptidomics meetings and combining all this with a superbly enjoyable experience.

    At the start of 2020 we were all excited by the prospect of another annual Congress – this time in Stockholm, Sweden. In a very timely manner and as the COVID pandemic was gripping the world the Stockholm local organising committee advised against a ‘face-to-face’ Congress. The decision was made to postpone the Stockholm meeting (to 2021) and hold a virtual Congress in 2020 – a first for HUPO.  A virtual Organising Committee (vOC) was assembled and worked tirelessly with colleagues from ICS (our core professional conference organiser) to plan and deliver HUPO Connect 2020. In addition, to the regular repertoire of proteomics research, the Congress provided an opportunity to highlight the key role proteomics has played in COVID-19 research. At a personal level, the chance to participate in the vOC; witnessing the development of our early stage career researchers, and the Congress supporting the development of a library of the recorded presentations were highlights of 2020. There have been many other proteomics highlights including, but not limited to, the publication of the High-Stringency Blueprint of the Human Proteome, the publication of the annual HPP metrics paper and the celebration of 20 years of the Human Protein Atlas.

    Of course, challenges (opportunities) remain for the continued development of proteomics and I’m very confident that HUPO under leadership of YuJu Chen will continue to catalyse the pace of proteomics successes. YuJu will be ably supported by the HUPO EC and, under the leadership of Rob Mortiz, the HPP EC.

    Finally, I’d like to encourage all members and especially existing and newly elected HUPO Council members to get involved in HUPO’s activities. The old adage – the more you put in the more you get out – is as true now as it ever was.

    Thank you all for giving me a wonderful opportunity and particularly to those who have guided and supported me in the last two years. It’s perhaps not wise to single out any individuals but here goes anyway….! I’d particularly like to thank Jenny van Eyk and Michelle Hill for their consistent and much valued wise counsel and support and Chelsea Prangnell for her support and willingness to share the benefit of her ‘HUPO experience’.

  • 12 Jan 2021 3:03 PM | Anonymous member (Administrator)

    Yu-Ju Chen, HUPO President, Institute of Chemistry, Academia Sinica, Taiwan

    It is truly a great honor and a big responsibility to serve as the HUPO president in the coming two years. Since the past January, I have joined the HUPO EC and witnessed the great efforts from the leadership team led by Past President Steve Pennington and Vice-President Susan Weintraub. Among the many impressive HUPO achievements, perhaps most notable and quite unique to everyone is the HUPO Connect 2020 – the very first virtual congress for HUPO. The HUPO leadership together with supports from HPP, committees, council members, speakers and sponsors have jointly turned the challenges of COVID-19 outbreak into a landmark congress in the history of HUPO. Big thank you to Steve and Sue for your contribution and congratulation to the achievements made in the past two years. From my personal view, this is the uniqueness of HUPO that we have devoted and passionate colleagues to create an inclusive and energetic infrastructure for promoting proteomics activities. I am looking forward to working with you all to enjoy proteomics activities and to translate it into knowledge in biology, health and disease as well as tools to impact our life.

    Despite the unexpected and devastating economic and social disruption caused by the COVID-19 outbreak, it indeed created an opportunity to demonstrate the global proteomic exploration to enhance our molecular understanding for the emerging disease and to facilitate development of new diagnostic and therapeutic strategies. Exciting researches are exemplified in the power of multidimensional data integrating proteomics with clinical data and machine-learning-based models for risk stratification of patients, construction of SARS-CoV-2 protein interaction network to reveal the pathogenesis mechanism as well as to identify targets for drug repurposing, identification of biomarkers and rapid development of high throughput diagnosis tools for the clinical trajectory of patients. In addition to continue to promote the International collaboration in infectious diseases from the HUPO initiative, I look forward to facilitate efforts in standardization of protocols and diagnosis methods and multi-nation clinical trial within the HUPO community. The example of COVID19 may also apply to other diseases to promote precision medicine for sustainable health.

    The Human Proteome Project (HPP) is well recognized as the signature for HUPO’s research activities. The release of “ A High-Stringency Blueprint of the Human Proteome” in 2020 established the legacy of the first decade of the HUPO HPP in defining the constitutions of the complex proteome with 90% coverage based on stringent criteria. I would like to express my great appreciation to the HPP leadership led by Gil Omenn, Mark Baker and Robert Moritz, advisory board and many colleagues who have contributed to HPP in the past years. Looking ahead, the human proteome blueprint is definitely the foundation of future proteomics research.

    Despite our many successes, there remains much to be done to demonstrate the utility of proteomics. To date, advancements of genomics have changed the face of biology and medicine. Despite the fact that proteins are the molecules to be targeted for many therapies, however, gene testing is gold standard and protein-based diagnosis is not well accepted as clinical assay yet. Stepping into the next 10 years of HPP, I believe that proteomics will take a similar path like genomics to create benefits of our life. To speed up the process, we can jointly define focused themes, reachable milestones and strategies to transform proteomics into utilizes in many aspects of life, such as clinical care, prevention medicine, precision agriculture, and food safety. 

    “If you want to go fast, go alone. If you want to go far, go together”- African proverb.

    This is my firm belief that joint wisdoms and collaborative efforts always inspire new ideas with success beyond the expectation of a single mind. After 20 years since the launch of HUPO in 2001, we are now stepping into the next phase of proteomics. It is time to redefine the forward-looking goals and strategic planning for HUPO to create impact to biology, health and society. I will continue the inclusive culture of HUPO and sincerely encourage our members and everyone who loves proteomics from different part of the world to work together and demonstrate the power of proteomics to impact our life in the future.

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