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  • 04 Mar 2024 6:56 AM | Anonymous member (Administrator)

    The HUPO Early Career Researcher (ECR) Committee is excited to present this year’s Poster Competition sponsored by Molecular Omics. All graduate students (Master’s and PhD), as well as postdocs, are invited to participate in the HUPO 2024 poster competition taking place October 20-24, 2024 in Dresden, Germany.

    To participate...graduate students and postdocs simply need to indicate in their abstract submission that they would like to participate in the competition. Fifteen abstracts from graduate students and fifteen abstracts from postdocs will be selected as finalists based on their quality.

    Posters will be evaluated during the conference by a jury. Winners in both categories (graduate students and postdocs) will each receive a cash prize of $200 USD and four runner-ups will each receive $100 USD thanks to Molecular Omics. All early career proteomics researchers are invited to participate!

    All early career proteomics researchers are invited to participate

  • 04 Mar 2024 6:51 AM | Anonymous member (Administrator)

    Building on the success of previous 3-Minute Thesis Competitions, the HUPO Early Career Researcher (ECR) Committee and the Human Proteome Project (HPP) team up once again to provide this engaging competition. Present your proteomics Ph.D. thesis topic in 3 minutes using a single static slide and in a format that can be understood by a general audience.


    To participate, simply submit a lay abstract via the HUPO 2024 abstract submission portal without scientific jargon that describes your Ph.D. thesis research topic. Abstract text should not exceed 300 words. Entrants must be enrolled in a Ph.D. program.


    Finalists who will be selected based on the quality of their abstracts, will have the exciting opportunity to compete in the final showdown, to be held during a dedicated session at HUPO 2024 in Dresden, Germany (October 20-24). Are you up for the challenge?

  • 04 Mar 2024 6:44 AM | Anonymous member (Administrator)

    Seize the opportunity to showcase your recent achievements in the dynamic field of proteomics! We invite early career researchers to apply for the 10th edition of the HUPO Early Career Researcher (ECR) Manuscript Competition, taking place at the HUPO 2024 World Congress in Dresden, Germany, October 20-24. This competition offers a unique platform for postdoctoral fellows, young clinicians, and junior faculty members to gain visibility within the proteomics community, emphasizing their significant contributions to the field.

    Three finalists will be selected to present their manuscript (published during the 2023 and 2024 calendar years), in an exclusive plenary session at HUPO 2024, where an expert committee will evaluate the oral presentations to determine the "Proteomics Highlight of the Year." The first-place winner will receive a cash prize of $1,000 USD, while two runner-ups will each be awarded $500 USD.

    Don't miss this chance to showcase your proteomics expertise and be recognized among peers at HUPO 2024!

    Unsure about applying? https://www.hupo.org/News/13322997Hear from last year’s finalist here, Dr. Pavel Sinitcyn about his experience at HUPO 2023 in Busan, South Korea.

    More information and details here about the competition, eligibility and how to submit on the HUPO website.

    Deadline to Apply: April 1, 2024

  • 01 Mar 2024 1:22 AM | Anonymous member (Administrator)

    Dr. Pavel Sinitcyn
    Morgridge Institute For Research, United States


    Pavel Sinitcyn is a distinguished Morgridge Interdisciplinary Postdoctoral Fellow at University of Wisconsin-Madison, conducting cutting-edge research in Dr.Joshua Coon’s lab. With a strong background in developing software solutions for proteomics data processing, Dr. Sinitcyn has played a pivotal role in developing tools such as MaxQuant, MaxDIA, Perseus, and Deep Proteomic Sequencing Methods.

    Dr. Pavel Sinitcyn was a finalist in the HUPO 2023 ECR Manuscript Competition, for which he presented his manuscript, “Global Detection of Human Variants and Isoforms by Deep Proteome Sequencing”, in a plenary session. To get the inside story, we asked Dr. Sinitcyn a few questions about his experience in the competition. Read what he had to say below!

    1. What is your current position and affiliation?
    I am a postdoctoral researcher in the Coon lab at University of Wisconsin-Madison, United States. In June 2024, I will be starting my own group at Utrecht University in The Netherlands

    2. How would you like your work to contribute to the field of proteomics?
    I would like to see a change in the definition of protein coverage in the field. Rather than merely discussing protein coverage as the number of detected proteins out of the many annotated protein-coding genes, we should consider coverage as the portion of amino acids covered by a few detected peptides. This shift will enable a more comprehensive quantitative measurement of sequence isoforms, small amino acid variations, and post-translational modifications on a global scale.

    3. What have you found in the HUPO community/congress?
    I greatly appreciate the international mindset of the HUPO community. This conference goes beyond the opportunity to listen to great talks/posters and meet colleagues and friends in one place; it allows for the exploration of the landscape of the field on a global scale, spanning various countries and regions.

    4. How was your experience/what did it mean to present your work at HUPO?
    I thoroughly enjoyed my experience presenting my work at HUPO, especially within the HUPO ECR community. Returning to HUPO is always a pleasure. The conference's well-tuned schedule and scale allowed for a comprehensive experience without the usual need to constantly choose between simultaneous must-visit sessions. The vibrant atmosphere of the poster session and bioinformatics hub added to the overall positive experience. And finally, attending this conference was particularly meaningful for me as it was the first one after the birth of my son, giving me the opportunity to fully participate in the session organized by Moms in Proteomics.

  • 31 Jan 2024 9:28 AM | Anonymous member (Administrator)

    Date: Wednesday February 28, 2024
    Time: 4pm GMT (5pm CET)

    Are you a Ph.D. student, postdoc, or early career researcher looking to get recognised for your work? Join the next HUPO Early Career Researcher online panel discussion, "Getting recognised for your work", at 4pm GMT (5pm CET) on Wednesday February 28.

    The panel will feature Dr. Laurent Gatto (Associate Professor of Bioinformatics, UCLouvain), Dr. Stacy Malaker (Assistant Professor of Chemistry, Yale University), and Dr. Juan Antonio Vizcaino (Scientist and Team Leader, Proteomics, European Molecular Biology Laboratory).

    This will be the perfect opportunity to ask any questions that you may have about getting recognised for your work and putting yourself in a favourable position for your future career.

    REGISTER HERE

  • 31 Jan 2024 8:51 AM | Anonymous member (Administrator)

    Date: April 24-26, 2024
    Location: Madrid, Spain

    The C-HPP is holding a workshop Madrid, Spain, at the National Center for Biotechnology, CSIC, Campus of the University Autónoma of Madrid, Darwin, 3, Spain.

    A workshop hotel is being organized where registrants can book and cover their own accommodation. The hotel will be near the train station for a short 15-minute ride to the University Autónoma.

    Registration and most meals and coffee are free and we invite members of the C-HPP, B/D-HPP, and HPP to register as soon as possible to help with planning.

    AGENDA

    The main foci for the Workshop are (i) short business meeting for reports and C-HPP Chromosome team updates.

    Preliminary Program

    Wednesday April 24
    13:00-14:00 Welcome Lunch
    14:00-17:00 Discussion on guidelines for assigning protein function for the Grand Challenge, and incorporating SWATH/DIA data into the HPP. With the loss of support of neXtprot, also to be discussed will be a new repository for HPP progress on completing the Human Proteome Project and where the data will reside for functional annotation of the Human Proteome.

    Thursday April 25
    09:00-13:00 Session One Welcome, the C-HPP Mission, contributing to the HUPO Grand Challenge.
    12:30-13:00 Invited speaker (TBA)
    13:00-14:00 Lunch
    14:00-18:00 Session Two
    14:00-15:30 Three invited speakers (TBA)
    15:30-16:00 Coffee
    16:00-18:00 Open Discussion on Mission of the C-HPP
    19:00 Tapas Dinner in Madrid Center

    Friday April 26
    09:00-13:00 Session Three
    09:00-10:00 Two invited speakers (TBA)
    10:00-10:30 Coffee
    10:30-13:00 Discussion on the Grand Project
    13:00 Campus Restaurant lunch and departure

    REGISTER HERE

  • 31 Jan 2024 8:47 AM | Anonymous member (Administrator)

    The hallmark update paper each year is the HPP Metrics publication, is now online, lead by Dr Gil Omenn and the leaders of neXTprot, the Peptide Atlas, the HPP, C-HPP and B/D-HPP:

    The 2023 Report on the Human Proteome from the HUPO Proteome Project”, by Gilbert S. Omenn,* Lydie Lane, Christopher M. Overall, Cecilia Lindskog, Charles Pineau, Nicolle H. Packer, Ileana M. Cristea, Susan T. Weintraub, Sandra Orchard, Michael H. A. Roehrl, Edouard Nice, Tiannan Guo, Jennifer E. Van Eyk, Siqi Liu, Nuno Bandeira, Ruedi Aebersold, Robert L. Moritz, and Eric W. Deutsch.

    ABSTRACT: Since 2010, the Human Proteome Project (HPP), the flagship initiative of the Human Proteome Organization (HUPO), has pursued two goals: (1) to credibly identify the protein parts list and (2) to make proteomics an integral part of multiomics studies of human health and disease. The HPP relies on international collaboration, data sharing, standardized reanalysis of MS data sets by PeptideAtlas and MassIVE-KB using HPP Guidelines for quality assurance, integration and curation of MS and non-MS protein data by neXtProt, plus extensive use of antibody profiling carried out by the Human Protein Atlas. According to the neXtProt release 2023-04-protein expression has now been credibly detected (PE1) for 18,397 of the 19,778 neXtProt predicted proteins coded in the human genome (93%). Of these PE1 proteins, 17,453 were detected with mass spectrometry (MS) in accordance with HPP Guidelines and 944 by a variety of non-MS methods. The number of neXtProt PE2, PE3, and PE4 missing proteins now stands at 1381. Achieving the unambiguous identification of 93% of predicted proteins encoded from across all chromosomes represents remarkable experimental progress on the Human Proteome parts list. Meanwhile, there are several categories of predicted proteins that have proved resistant to detection regardless of protein-based methods used. Additionally there are some PE1−4 proteins that probably should be reclassified to PE5, specifically 21 LINC entries and ∼30 HERV entries; these are being addressed in the present year. Applying proteomics in a wide array of biological and clinical studies ensures integration with other omics platforms as reported by the Biology and Disease-driven HPP teams and the antibody and pathology resource pillars. Current progress has positioned the HPP to transition to its Grand Challenge Project focused on determining the primary function(s) of every protein itself and in networks and pathways within the context of human health and disease.

  • 30 Jan 2024 5:54 AM | Anonymous member (Administrator)

    The HUPO Early Career Researcher (ECR) Committee is delighted to welcome Pathmanaban Ramasamy. Keep reading to know more about him!

    Pathmanaban Ramasamy (Paddy) is a junior post-doc in the CompOmics group at Ghent University in Belgium. During his joint Ph.D. program between Ghent University and Vrije Universiteit Brussel, he leveraged his expertise in structural bioinformatics and proteomics informatics to unravel the role of local amino acid interactions in protein folding, fold stability, and the location of post-translational modifications (PTMs). He endeavors to unravel the "where, how, and why" of protein PTMs through a comprehensive large-scale investigation that spans these modifications within sequence, structure, and biophysical contexts.

    He has been extremely active in bringing the MS proteomics and structure communities together at the European scale, investing heavily in an ELIXIR Europe-funded cross-over study between the three key communities: the 3D-BioInfo (protein structure), Intrinsically Disordered Proteins, and MS Proteomics communities. Paddy is enthusiastic about becoming a member of the HUPO-ECR and looks forward to actively contributing to the support of young proteomics researchers through his involvement with HUPO-ECR and YPIC.

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