The HUPO Education and Training Committee is excited to announce a new webinar series focused on the critical role of proteomics in Clinical investigation. This series will have 6 webinars at ~1 month intervals and bring together leading experts to discuss the latest advancements, challenges, and opportunities in applying proteomics to improve human health. This webinar series is designed for researchers, clinicians, and anyone interested in learning more about the exciting field of clinical proteomics.
First Speaker: Prof. Ruben Luo, Assistant Professor of Pathology at Stanford Medicine https://med.stanford.edu/profiles/rubenluo
Title: Translation of Mass Spectrometry-Based Proteomic Research to Clinical Diagnostic Practice
Date: Wednesday 26th February 2025
Time: 11am PST / 2pm EST / 7pm UTC / 8pm CET / 3am CST (27th) / AEDT 6am (27th)
Registration: https://us06web.zoom.us/webinar/register/WN_6clGWevzT4W-mStOXfcB5w
Abstract
Protein diagnostic biomarkers are increasingly measured in clinical laboratories to aid disease diagnosis. However, conventional clinical tests typically emphasize quantitation and often overlook other crucial characteristics of these biomarkers—such as their structural features and proteoforms—that could provide more specific and accurate diagnostic insights. By incorporating proteomics into clinical testing, it is possible to capture these additional details, thereby broadening the scope and precision of clinical diagnosis. In this webinar, we will discuss the requirements and guidelines for clinical tests, review methodologies for clinical proteomic assays, and present examples of clinical proteomic assays including the illustration of the process from biomarker discovery to clinical validation.
Speaker Bio:
Ruben Y. Luo, PhD, DABCC, FADLM is an Assistant Professor of Pathology at Stanford University and the Associate Director of Clinical Chemistry Laboratory at Stanford Health Care. He received PhD in chemistry from Stanford University, worked in the clinical diagnostic industry for several years, and then completed clinical chemistry fellowship at the University of California San Francisco. Dr. Luo is dedicated to innovations in clinical diagnostics. His research focuses on (1) discovering the clinical diagnostic value of molecular characteristics of protein biomarkers, and (2) applying top-down mass spectrometry and label-free optical sensing immunoassays to characterization and accurate measurement of biomarkers. He has been an active member and conference speaker in the international clinical chemistry and mass spectrometry communities, e.g., Association for Diagnostics and Laboratory Medicine (ADLM; formerly American Association for Clinical Chemistry, AACC), American Society for Mass Spectrometry (ASMS), Mass Spectrometry & Advances in Clinical Lab (MSACL). His research awards include 2022 AACC George Grannis Award for Excellence in Research and Scientific Publication, 2020 American Society for Clinical Pathology (ASCP) “40 Under Forty” Honoree, etc. He currently serves as an associate editor of JMSACL and an editorial board member of Scientific Reports.
Previous webinars:
You can find a playlist with videos for Series 1 and 2 of the HUPO ETC Webinar focused on Scientific Writing and Focus on Technology here: https://bit.ly/etc_webinars
