DATE: Wednesday, January 24, 2024
TIME: 6am PST / 9am EST / 3pm CET
LOCATION: Zoom (link to follow upon registration)
SPEAKER: Daniel DeBord, PhD
WEBINAR DESCRIPTION:
Protein identification is of fundamental importance in many areas of proteomics. Its applications include determining the presence or absence of an expected protein in a sample of interest, identifying an unknown protein present in a biological sample, and identifying a protein responsible for biochemical activity in an isolated protein fraction. In some cases, mass spectrometry or affinity-based methods may be suitable options, but these methods can face substantial challenges. Scientists need the ability to identify and measure peptide modifications, structures, and impurities more definitively and faster. Driven by structures for lossless ion manipulation (SLIM) technology, the MOBIE® instrument’s high-resolution ion mobility mass spectrometry platform separates and identifies the most challenging molecules with unprecedented resolution without compromising speed. By combining the MOBIE® platform’s high-resolution ion mobility mass spectrometry (HRIM-MS) data with liquid chromatography, more accurate separation and identification of impurities and posttranslational modifications (PTMs) can be achieved, reducing run times and costs.
LEARNING OBJECTIVES:
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Attendees will learn Attendees will learn about (1) separation science, including SLIM (structures for lossless ion manipulation) and high-resolution ion mobility (HRIM); (2) the trade-off between speed, resolution, and reproducibility; and (3) accuracy for targeted lipidomics, peptide characterization, glycan analysis, PFAS, and many other workflows.
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Why Attend? AAttendees will uncover insights into how to incorporate HRIM into traditional analytical workflows and where the technology is used to answer clinical questions.
SPEAKER BIO:
Daniel currently serves as the Vice President of R&D for MOBILion Systems, Inc. In this role, he leverages his 15 years of experience developing novel analytical instrumentation to address challenges across a range of application spaces. Daniel received a BS in Chemistry from Campbell University and a Doctorate in Analytical Chemistry from Texas A&M University. Prior to starting work with MOBILion, he served as the Chemistry Manager and lead developer for 1st Detect Corporation, a company that develops miniaturized mass spectrometry-based detection systems for a variety of markets. Daniel also worked as a staff Research Scientist and Associate Director of the Mass Spectrometry Facility at Florida International University and as an LC‒MS chemist for BASF. For the past 10 years, Daniel has focused on developing ion mobility technologies such as trapped ion mobility spectrometry (TIMS) and structures for lossless ion manipulation (SLIM) and exploring how these new techniques can be coupled with traditional LC‒MS instruments to access higher performance in fields such as proteomics and biopharma characterization.
REGISTER HERE
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