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Infectious Disease Initiative

The Human Infectious Diseases HPP initiative (HID-HPP) is a world-wide coordinated enterprise to encourage and promote collaboration between scientists working on proteomics studies related to infectious diseases caused by virus, bacteria, fungi and parasites.

Infectious diseases constitute one of the leading causes of illness and death throughout the world, in particular in low income countries. Lower respiratory infections, HIV/AIDS and diarrheal diseases are ranked in the top ten causes of death globally, whereas malaria and tuberculosis are two of the major ten causes of death in low income countries. In developed countries infectious diseases are also important in immunosuppressed patients and transplant recipients. New diagnostic tests, therapeutic agents and vaccines are required to control these infectious diseases. International collaboration of scientists working in infectious diseases and proteomics is therefore essential to promote these researches.

The HID-HPP initiative was first devised during the 13th HUPO world congress held in Madrid 2014 and eventually settled during the Vancouver 2015 HUPO congress.

Current lines of work:

  • How can the scientists working in proteomics of infectious diseases collaborate?
  • Development of SRM methods for detection and quantification of human and microbial proteins
  • Detection and quantification of these proteins by affinity or antibodies based technologies
  • Characterization of microbial-host protein interaction networks
  • Identification of host factors as antimicrobial therapeutic targets
  • Building of a web site to freely access data
  • Dissemination of HID-HPP activities (reports, special issues, etc.)
  • Organization and future actions

Websites and links:

Papers:

  • Published special issue on “Trends in Microbial Proteomics” in Journal Proteomics (2014).
  • Published special issue on “Virology meets Proteomics” in Proteomics journal (2015).
  • Published special issue on “Proteomics in Infectious Disease” in Molecular and Cellular Proteomics journal (2017)
  • Special issue on “Proteomics in Infectious Diseases” in Journal of Proteomics (deadline for submission is 15 December 2016)

Leadership:

Ileana Cristea, Chair | Princeton University, USA, 
Concha Gil, Co-Chair | Complutense University of Madrid, Spain.

For more information or participation opportunities please contact office(at)hupo.org.



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