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The Human Proteome Organization (HUPO) condemns, in the strongest terms, the military invasion of Ukraine by the Russian Federation, and deplores the resulting loss of life and humanitarian impact.

We urge all HUPO members to offer opportunities for support, scientific research and collaboration to Ukrainian scientists, whether abroad,  displaced or under threat in their home country, and recommend highlighting these opportunities through HUPO channels as well as portals like https://scienceforukraine.eu/.

As a global scientific organisation, HUPO supports the principles of the universality of science (https://council.science/5-universality-of-science). It is therefore key to note that our colleagues in Russia will maintain their individual positions and roles within HUPO, and will continue to have, as individuals, full access to all HUPO information and activities. Indeed, as a scientific organisation, with engagement, inclusivity, and transparency at our core, we do not condone any actions by anyone against any individuals simply because of their country of origin or residence.

The May HUPOST is now available!  Check out lots of interesting info and articles...

April HUPOST is now available -- Catch all the important info and updates!

On Friday, May 13, following the 3-day 2nd Joint Meeting of Spanish, French and Portuguese Proteomics Societies, the Chromosome Centric Human Proteome Project (C-HPP) announces the 25th C-HPP Workshop on “Accelerating the HPP Grand Challenge”.

This satellite workshop is open and free to all participants of ProteoVilamoura. Agenda: https://www.hupo.org/News/12690881

If you want to attend, just register on our website: https://proteo-vilamoura.sci-meet.net/ by accessing “FEEs” on your personal area, select the C-HPP Satellite Workshop and save.

Location: Forum Dom Pedro Vilamoura Main Conference Hall

Date:  Friday May 13, 2022   Time: 14:00 – 17:00

Agenda:

• Welcome by Chris Overall, Chair C-HPP 14:00-14:05
• Lydie Lane, Co-Chair C-HPP, Chair Chromosome 2 Team:  "Update on Progress in Completing the Human Proteome, neXtprot Release 2022" (20 + 5 minutes)" 14:05-14:30
• Gong Zhang, Chair Chromosome 8 C-HPP Team: "The discovery, function and evolution of the hidden human proteome translated from "non-coding RNAs" (20 + 5 minutes) 14:30-14:55
• Marina Gay:  "How Top-down Proteomics Can Contribute to the HPP" (20 + 5 minutes) 14:55-15:20
• Charles Pineau:  "The HPP Grand Challenge" (20 + 5 minutes) 15:20-15:45
• 75 minutes Open Discussion and Goal Setting, Chairs Chris Overall and Charles Pineau including the use of DIA for missing proteins with Ulrich auf dem Keller, Chair Chromosome 21, 15:45-17:00
• Meeting Close 17:00
• Refreshments and dinner at a local restaurant, at own expense.

The conference hotel and nearby hotels have special rates for ProteoVilamoura participants. You must make your reservation directly with the hotels with the reservations codes listed here: https://proteo-vilamoura.sci-meet.net/travel-accommodation

The ECR is delighted to welcome several new members from all over the world. They will play key organizing roles in ECR activities such as mentoring sessions, networking hours, online panel discussions, competitions and more.

Dr. Sayantani Chatterjee is a Post-Doctoral Associate in Prof. Joseph Zaia’s research group in Boston University School of Medicine in Boston, Massachusetts, USA. Her current research focuses on exploring viral glycoproteomics, particularly of influenza and SARS-CoV-2 viruses, using high-throughput mass spectrometry, to aid in the development of effective therapeutics. Previously, she completed her PhD under the supervision of Dr. Morten Thaysen-Andersen from Macquarie University, Sydney, Australia where she investigated the structure, function, and involvement of mannose-terminating glycoproteins in cancer, innate immunity and pathogenic infections.

Ireshyn Govender is a senior researcher in the Molecular Diagnostics and Omics group at the Council for Scientific and Industrial Research (CSIR), South Africa. He started his career at CSIR in 2013 as a candidate researcher, where his research focused on clinical proteomics in HIV/AIDS-based precision medicine. His Ph.D. was completed in 2019 at the University of the Witwatersrand. Ireshyn is also an application specialist at ReSyn Biosciences where he develops novel sample preparation workflows for biofluid-based clinical proteomics. He is a member of clinical research groups that use proteomics to address diseases that are prominent in South Africa and underrepresented populations by identifying prognostic and/or diagnostic protein biomarker panels. He is also an executive committee member of the South African Association for Mass Spectrometry (SAAMS).

Charlotte Hutchings is a PhD student in Kathryn Lilley's laboratory at the University of Cambridge. Having completed her BSc and MSc at Imperial College London, Charlotte's primary interest lies in the optimization of gene therapy vectors. It was this interest that led Charlotte to enter the world of proteomics where she now applies novel spatial proteomics methods to understand the mechanism by which adeno-associated viral vectors (used in approved gene therapies) are secreted from HEK293 producing cells. The aim of this work is to optimize the manufacturing of such vectors in collaboration with AstraZeneca. Outside of her project, Charlotte participates in public outreach events and acts as a STEM Ambassador for the North East region of England. She is also a member of the British Society for Proteome Research and the Biochemical Society and is continuing to expand her network. 

Santosh Misal is a Proteomics Scientist at the Laboratory of Malaria, Immunology, and vaccinology (LMIV), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda MD, USA. He manages a small proteomics facility and provides support to the LMIV investigators for the malaria biomarker discovery and vaccine development pipeline. He utilizes various proteomics approaches including chemical labeling, crosslinking, and single-cell protein analysis to identify parasite protein targets for vaccine development. Before joining NIH, he was a postdoctoral scientist at Brigham Young University and Indiana University Bloomington. Santosh obtained his Ph.D. degree in Biochemistry from Savitribai Phule Pune University, India with a strong interest in protein analysis.

Sri Ramarathinam has over 15 years of cumulative experience in proteomics and immunopeptidomics. After completing Master of Biotechnology from RMIT University, he worked as a Research Assistant at the University of Melbourne for four years in proteomics, before completing PhD in HIV immunobiology from Monash University. He is currently working as a post-doctoral research fellow at the immunopeptidomics lab headed by Prof Tony Purcell at Biomedicine Discovery Institute (Monash). His research interests include development of new methodologies to address questions in virology, antigen processing and presentation, cancer and autoimmunity. He is also passionate about ECR well-being and is part of institute- and faculty-level ECR committees.

March issue of the HUPOST is now available. Lots of updates to check out!

Catch up on HUPO news with the February HUPOST! 

The HUPO ECR Initiative is excited to welcome two new members to its organization: Jessica Del Castillo Alferez, a Ph.D. candidate at the University of Utrecht in the Netherlands, and Isabell Bludau, a postdoctoral fellow at the Max Planck Institute in Germany. Learn more about these two up-and-coming researchers below.

Jessica Del Castillo Alferez is a Ph.D. candidate at Sanquin Research Amsterdam and the University of Utrecht, Netherlands. Her research focuses on the development of plasma peptidomics and proteomics approaches to unravel fundamental aspects of haemostasis. She obtained her bachelor’s degree in Biochemistry at UDLAP, Mexico with a one-year exchange at McGill University, Canada. After this, she moved to the Netherlands where she completed a Master’s program in Molecular Medicine at the University of Groningen. During her Master’s internship, she entered the field of clinical proteomics while investigating proteomic adaptations of asymptomatic MCADD. Jessica is part of the Symphony Consortium, which aims to improve treatment for bleeding disorders by addressing interindividual variation in bleeding tendency. As part of Symphony, her Ph.D. project seeks to link the proteome to the bleeding phenotype with the use of plasma and blood cell profiles to study modifiers of haemostasis.

Isabell Bludau is a postdoctoral fellow in the lab of Prof. Matthias Mann, at the Max Planck Institute of Biochemistry near Munich. She is specialized in computational proteomics and systems biology. During her Ph.D. with Prof. Ruedi Aebersold at ETH Zurich, Isabell developed computational methods for analyzing large-scale proteomics data. She specifically worked on the detection and quantification of protein complexes. Recently, Isabell’s work focused on the inference of proteoforms and their crosstalk. Isabell’s PhD thesis was awarded the ETH silver medal and her postdoctoral research is supported by a Postdoctoral Mobility fellowship of the Swiss National Science Foundation. Since 2020, Isabell is a member of the organizing committee of the ISCB’s Community of Special Interest (COSI) on Computational Mass Spectrometry (CompMS), which organizes conference sessions and aims to build a community of scientists working in CompMS.

Catchup on the latest HUPO updates in the November HUPOST:

https://conta.cc/3CI9vv5

Founded in 2001, HUPO turned 20 this year! We are celebrating 20 years of excellent scientific conferences, community engagement, science advocacy, and advanced education! The annual HUPO world congress has been a key event for proteomics scientists since 2002, and has continued through financial and recent pandemic challenges to this year. HUPO community-centric projects, from the Human Plasma Proteome Project of 2001 to the HPP Grand Challenges of today provide cristallisation points for intensive global collaborations, advancing proteomics science and networking. Strong engagement of early career researchers is culminating in five ECR-organised sessions and five days of online training at this year's HUPO ReCONNECT!

For an interactive look through the intertwined history of HUPO and proteomics, check out https://www.hupo.org/Proteomics-Timeline, for a look at the future of proteomics attend our week-long birthday party, the HUPO ReCONNECT congress at https://hupo2021.org/. We're looking forward to virtually meeting you at www.hupo2021.org!