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Post-doctoral scholar in proteomics of cancer immunotherapy

11 Jan 2022 1:01 PM | Anonymous

Title: Post-doctoral scholar

Institution: University of California, San Francisco - Wiita Lab

Location: San Francisco, California, USA

Availability: Jan 2022

Position: We are currently recruiting a post-doctoral scholar with experience in mass spectrometry-based proteomics to help us advance our mission of discovering new targets and developing new immunotherapies for blood cancers.

Specifically, our group has developed new methods of profiling the cancer cell surface using mass spectrometry-based proteomics to identify immunotherapy targets and then using novel, fully in vitro-display technologies to develop nanobody binders that are highly active in cellular therapy approaches (for example: Nix et al., Cancer Discovery (2021))

We now seek a motivated post-doc to work on a new project integrating chemical biology and mass spectrometry strategies to identify and new classes of immunotherapeutic targets in cancer, and then develop new therapies against these targets. This position is ideal for a scientist trained in mass spectrometry who seeks to broaden their horizons into therapeutic development and protein engineering.

Qualifications: PhD-level experience in mass spectrometry-based proteomics is required. Experience in bioinformatics or computational biology is advantageous. Experience in biological and biochemical techniques such as cell culture, cloning, PCR, Western blotting, recombinant protein expression/purification, transfection/lentiviral transduction, and/or cytotoxicity assays are also a plus.

A track record of scientific accomplishment, including at least one first-author original research publication in a peer-reviewed journal, is required. Strong oral and written communication skills in English are required.

Environment: We have ongoing collaborations with leading protein engineering and cellular therapy groups at UCSF, the Parker Institute for Cancer Immunotherapy, and the UCSF Living Therapeutics Initiative to enhance the scope and impact of this work. The goal of this work is both to make new scientific discoveries but also ultimately impact the lives of patients.

Our group is located in beautiful San Francisco, California. UCSF is one of the premier academic medical centers in the world, excelling in both basic science and clinical research. We are a multidisciplinary research group and our interests span from the basic to translational realms across a number of conditions, as well as new technology development combining chemical-based enrichment and quantitative proteomics. We offer competitive salary in line with cost-of-living in the Bay Area. We are fortunate to have numerous sources of funding including federal agencies and private foundations supporting our work. We are also fortunate to have extensive collaborations with other world-leading scientists across UCSF, as well as access to world-class core facilities to accelerate discoveries in biomedical research. Furthermore, our clinical collaborations allow for rapid translation of discovery from the bench to bedside. In addition, all mentorship and project design within our group is customized for the scholar's career goals, whether entering academia or industry. Prior post-doctoral scholars in the Wiita group have moved on to senior/principal Scientist positions in biotechnology firms or tenure-track academic positions.

Funding: This is a fully funded position with salary and benefits for at least two years guaranteed.

Website: https://wiitalab.ucsf.edu

Applicant Instructions: Well-qualified applicants should send a CV, cover letter, and contact information for two references to arun.wiita@ucsf.edu.

The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status.






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