Human Antibody Initiative
Overview of Project
The mission of the Human Antibody Initiative (HAI)
aims to promote and facilitate the use of antibodies for proteomics
research. The initiative consists of two separate activities; (1) the
generation of a catalogue of validated antibodies from many different
sources and (2) a protein atlas for the expression and localization of human
proteins in normal and disease tissue. The two separate activities have as
their primary deliverables to generate databases with free public
accessibility. The Antibody Resource database (www.antibodypedia.org)
is aimed to produce a comprehensive catalogue of validated antibodies
towards human proteins. This initiative depends on input from a large number
of academic groups and commercial companies. The Protein Atlas initiative (www.proteinatlas.org)
is aimed to provide comprehensive and annotated database of high-resolution
images showing tissue profiles in normal and cancer tissues. Both databases
will be open to the public without restriction (no passwords).
Collaborations with other Initiatives
- Antibodies developed in the Plasma Proteome Project will be included in the database
- Antibodies included in our database will be used to cross reference those for several of the subprojects in the Human Liver Proteome Project (HLPP). In addition, any antibodies created in the HLPP will be added to our database.
Future meetings with dedicated sessions
TBA
Key Documents Related to Activities
- Notes from 7th HAI workshop, September 8, 2011 (Geneva, Switzerland)
- 2010 Report to the HUPO Council from the Human Antibodies Initiative
- Notes from 6th HAI workshop, September 26, 2009 (Toronto, Canada)
- September 27, 2009 Report to HUPO Board of Directors
- HUPO 8th Annual World Congress, Toronto 2009 - View Preliminary agenda
- Agenda for the 5th HAI Workshop HUPO 7th Annual World Congress, Amsterdam 2008
- Notes from the 4th HAI Workshop, October 7, 2007 in Seoul
- Agenda for the 4th HAI Workshop HUPO 6th Annual World Congress, Seoul 2007
- Agenda for the August 27, 2005 HAI Workshop
- Agenda for the October 29, 2006 HAI Workshop
- Proposal to HUPO council, April 2005
- Reference: Uhlen M, Ponten F. Antibody-based Proteomics for Human Tissue Profiling. Mol Cell Proteomics. 2005 Apr;4(4):384-393
Website Link
