The Pre-Congress Activities will take place on Saturday
October 28 and Sunday October 29, 2006.
WORKSHOPS, HUPO INITIATIVE MEETINGS, AND PANEL DISCUSSIONS (Open to all Congress registrants) |
|
08:30-11:30 |
HUPO PSI WORKSHOP
Co-Chairs: Ruedi Aebersold, Randy Julian, Henning Hermjakob
Room 201, level 2, Convention Center |
| The Proteomics Standards Initiative (PSI) defines community standards for data representation in proteomics to
facilitate data comparison, exchange and verification. |
| 8:30-8:45 |
Introduction |
| 8:45-9:30 |
Keynote |
| 9:30-10:00 |
Minimum Reporting requirements for Proteomics: MIAPE; Pierre-Alain Binz |
| 10:00-10:30 |
Panel discussion: Minimum Reporting Requirements: Essential Component of
Proteomics |
| 10:30-10:45 |
BREAK. Refreshments are on level 2 |
| 10:45-11:00 |
The PSI MI Standard for Molecular Interactions; Sandra Orchard |
| 11:00-11:15 |
Standards for Mass Spectrometry; Randy Julian |
| 11:15-11:30 |
The PSI Standard for Gel Electrophoresis; Andy Jones |
|
|
| 08:30-11:30 |
HUPO PROTEIN TEST SAMPLE STANDARDS/NIST WORKSHOP
Co-Chairs: John R. Yates III and Alexander Bell
Room 202, level 2, Convention Center |
HUPO is leading the effort to create protein test standards for calibration of methods and techniques used in
proteome studies. Protein test standards can take a variety of forms including simple protein mixtures,
phosphoprotein mixtures, glycoprotein mixtures, and complex protein mixtures. Recent work on protein test
standards will be discussed in this forum including evaluations of protein mixtures for specific types of analyses and
suggestions for future protein test standards. |
| 08:30-09:00 |
TBA |
| 09:00-09:30 |
Dale Peluso; Sigma-Aldrich |
| 09:30-10:00 |
Alexander Bell |
| 10:00-10:30 |
TBA, Invitrogen |
| 10:30-11:00 |
John R. Yates III |
|
|
| 08:30-11:30 |
HUPO BIOMARKER CARDIOVASCULAR WORKSHOP
Co-Chairs: Mike Dunn, Jennifer Van Eyk, and Peipei Ping
Room 203, level 2, Convention Center |
Sat Oral D
08:30-08:50 |
Human Plasma Angiotensin Converting Enzyme-2 (ACE2): A Novel
Cardiovascular Disease Biomarker? A. Ian Smith1; Fiona Warner1; Mike
Yarski1; Jay Manohar2; Louise Burrell2; Rebecca Lew1; 1Monash University,
Melbourne, Australia; 2University of Melbourne, Melbourne, Australia .....................1302 |
Sat Oral D
08:50-09:10 |
A New Approach to Apolipoprotein Profile Analysis for Clinical Studies;
Emelita Breyer1; Kirtan Koticha1; W. Virgil Brown1; Mary Robinson2; 1Emory
University, Atlanta, Georgia; 2Centers for Disease Control, Atlanta, Georgia ...........1139 |
Sat Oral D
09:10-09:30 |
Circulating Human Monocytes in the Acute Coronary Syndrome Express a
Characteristic Proteomic Profile; Maria G. Barderas; Veronica M. Darde;
Fernando de la Cuesta; Alberto Lazaro; Julio Gallego-Delgado; Mari Carmen
Duran; Jose Tuñon; Jesus Egido; Fernando Vivanco; Fundacion Jimenez Diaz,
Madrid, Spain ...............................................................................................................1168 |
| 09:30-09:50 |
BREAK. Refreshments are on Level 2
SESSION RESUMES: Chair: Mario Hugo Genero |
Sat Oral D
09:50-10:10 |
Considerations for Proteomics’ Activities for the Development of Novel in
vitro Diagnostics; Frank Vitzthum; Dade Behring Marburg GmbH,
Marburg, Germany .......................................................................................................1248 |
Sat Oral D
10:10-10:30 |
Diffractive Optics Technology (dot™): A Novel Detection Platform for
Multiplex Biomarker Assay Development and Implementation; Paul Smith;
V Borisenko; W Hu; P Tam; I Chen; S Kumaraswamy; D Wong; W Ausserer; J-F
Houle; Axela Biosensors Inc., Toronto, Canada ..........................................................1385 |
Sat Oral D
10:30-10:50 |
Comparative Proteome Analysis to Study the Blood Platelet Storage Lesion;
Peter Schubert; Jonathan N. Thon; Marie Duguay; Katherine Serrano; Shujun Lin;
Dana V. Devine; Juergen Kast; University of British Columbia, Vancouver, BC ........1142 |
Sat Oral D
10:50-11:10 |
Novel Strategies to Improve Differential Proteome Analysis; Severine A.
Patat1; Cameron O. Scarlett1; Ryan M. Danell2; W. Cam Patterson1; Christoph H.
Borchers1; 1University of North Carolina at Chapel Hill, Chapel Hill, NC;
2Danell Consulting, Greenville, NC..................................................................................97 |
| 11:10–11:30 |
Panel Discussion: 1) Missions, 2) Study Design, 3) Database, 4) Web Site, 5)
Working Groups. Moderators: Mike Dunn and Robert E. Gerszten |
|
|
| 08:30-11:30 |
HUPO HBPP WORKSHOP ON STANDARDIZATION ISSUES IN PROTEOMICS:
PERSPECTIVES FROM VENDORS
Co-Chairs: Friedrich Herberg, Howard Gutstein, and Helmut E. Meyer
Room 104 A, Lobby level, Convention Center |
| The results of the HUPO BPP pilot studies have shown that a critical evaluation of techniques and strategies in
proteomics is necessary and essential for future reliability. In this session, company representatives and bioinformaticians
will present and discuss their point of view in regard to the need for standardization. |
| 08:30-8:50 |
Welcome Address; Friedrich Herberg
Lessons to Be Learned from HBPP Studies; Christian Stephan
Vendor Presentations |
| 08:50-09:10 |
Alexander Jung; Applied Biosystems |
| 09:10-09:30 |
Detlev Suckau; Bruker Daltonics |
| 09:30-09:50 |
James Langeridge; Waters |
| 09:50-10:10 |
Gunter Thesseling; GE Healthcare |
| 10:10-10:30 |
Stefan Lofas; Biocore |
| 10:30-10:55 |
Lennart Martens; EBI |
| 10:55-11:20 |
Discussion and Closing Remarks; Katrin Marcus & Helmut E Meyer |
|
|
| 08:30-11:30 |
NIDCR: HUMAN SALIVARY PROTEOME WORKSHOP
Co-Chairs: David Wong and Joseph Loo
Room 104 B, Lobby level, Convention Center |
| 08:30-8:50 |
Larry Tabak; NIDCR |
| 08:50-9:10 |
Susan Fisher; UCSF |
| 09:10-9:30 |
John R. Yates III; Scripps |
| 09:30-10:00 |
Joe Loo; UCLA |
| 10:00-10:20 |
David Wong; UCLA |
| 10:20-10:40 |
Gilbert S. Omenn; University of Michigan |
| 10:40-11:30 |
Panel Discussion |
|
|
| 08:30-11:30 |
NIA WORKSHOP ON PROTEOMICS UNRAVELING THE SECRETS OF AGING:
CHALLENGES AND SOLUTIONS
Chair: Satya Saxena
Room 104 C, Lobby level, Convention Center |
Sat Oral G
08:30-08:50 |
Proteomic Strategies for Aging and Age-Related Disorders; Satya P. Saxena;
National Institute on Aging, Baltimore, MD.................................................................1232 |
Sat Oral G
08:50-09:10 |
An Integrated Bioinformatics System for Functional Analysis; Cathy H. Wu;
Georgetown University Medical Center, Washington, DC, 20007...............................1235 |
Sat Oral G
09:10-09:30 |
Molecular Alterations in Thymocytes with Progressive Aging; Ana Lustig1;
Ankita Saxena1; Cathy H. Wu2; Satya Saxena1; Dennis D Taub1; 1National
Institute on Aging, Baltimore, MD; 2Georgetown University Medical Center,
Washington, DC............................................................................................................1236 |
| 09:30-10:00 |
BREAK. Refreshments are on Level 2 |
Sat Oral G
10:00-10:20 |
Post-translational Modifications of Human Premature Aging Proteins;
Tomasz Kulikowicz; Wen-Hsing Cheng; Satya Saxena; Vilhelm A. Bohr;
National Institute on Aging, Baltimore, MD.................................................................1237 |
Sat Oral G
10:20-10:40 |
Identification of New Genes Involved in Genomic Instability Diseases by
Protein Complex Purification and Mass Spectrometry; Amom Ruhikanta
Meetei1; Jinhu Yin1; Annette Medhurst2; Chen Ling1; Yutong Xue1; Satya
Saxena1; Maureen Hoatlin3; Hans Joenje2; Johan de Winter2; Johan de Winter2;
Weidong Wang1; 1National Institute on Aging, Baltimore, MD; 2VU University
Medical Center, Amsterdam, The Netherlands; 3Oregon Health and Science
University, Portland, OR ..............................................................................................1243 |
| 10:40-11:30 |
Panel Discussion. Moderators: Weidong Wang and Satya Saxena |
|
|
Sunday, October 29, 2006
|
| 09:00-17:00 |
EDUCATION DAY TWO. Registration is required with green name badge.
Regency Ballroom BC, Level 3, Hyatt Hotel |
| 09:00-10:00 |
Antibodies; Matthias Uhlen,
Royal Institute of Technology, Stockholm, Sweden |
| 10:00-11:00 |
Protein and Antibody Arrays; Dolores Cahill;
Conway Institute University College, Dublin, Ireland |
| 11:00-12:00 |
MALDI Peptide Mass Fingerprinting; Peter Roepstorff;
University of Southern Denmark, Odense, Denmark |
| 12:00-13:00 |
LUNCH. Lunch provided in the Beacon Ballroom, level 3, Hyatt Hotel |
| 13:00-14:00 |
Peptide Sequencing with LC-ESI MS/MS; Tine Thingholm;
University of Southern Denmark, Odense, Denmark |
| 14:00-15:00 |
PTM-Proteomics: Phosphoproteomics; Ole N. Jensen;
University of Southern Denmark, Odense, Denmark |
| 15:00-16:00 |
PTM-Proteomics: Glycoproteomics; Martin Larsen;
University of Southern Denmark, Odense, Denmark |
| 16:00-17:00 |
Bioinformatics for Proteomics; Pierre-Alan Binz;
Swiss Institute of Bioinformatics, Geneva, Switzerland |
| 17:00-18:00 |
Target Discovery and Validation in Clinical Proteomics; Jan Schnitzer;
Sidney Kimmel Cancer Center, San Diego, CA |
|
|
| 08:30-15:00 |
HUPO CLINICAL DAY. SPONSORED BY INVITROGEN
Registration is required with blue name badge.
Long Beach Convention Center |
| 08:30-10:00 |
PLENARY SESSION I: DIAGNOSTICS AND DRUG DEVELOPMENT:
HOW PROTEOMICS IS PART OF THE ANSWER
Co-Chairs: Scott D. Patterson and Denis Hochstrasser
Ballroom A, level 2, Convention Center |
Sun Oral B
08:30-09:00 |
Exposure Response Relationships in Early Drug Development using
Multiplexed Proteomics Assays; Scott D. Patterson; Amgen Inc.,
Thousand Oaks, CA ......................................................................................................1301 |
Sun Oral B
09:00-09:30 |
Systems Pharmacology: Using ‘omics Platforms to Understand Disease;
Michael Luther; Glaxo SmithKline |
Sun Oral B
09:30-10:00 |
Antibody-Based Vascular Targeting: From Target Discoevry to Clinical
Trials; Dario Neri, ETH-Zurich, Switzerland ..............................................................1435 |
| 10:00-10:30 |
BREAK. Refreshments are on Level 2 |
| 10:30-12:00 |
PLENARY SESSION II:
PROTEOMICS AND CLINICAL DIAGNOSTICS: PROBLEMS AND POSSIBILITIES
Co-Chairs: Denis Hochstrasser and Scott D. Patterson
Ballroom A, level 2, Convention Center |
Sun Oral C
10:30-11:00 |
Proteomic Based Biomarker Discoveries: Opportunities and Challenges;
Denis Hochstrasser; Geneva University and Hospital, Switzerland |
Sun Oral C
11:00-11:30 |
Cancer Proteomics: The Future Diagnostics for Clinical Chemistry;
Daniel W. Chan; Center for Biomarker Discovery, Johns Hopkins Univ,
Baltimore, MD ..............................................................................................................1325 |
| Sun Oral C 11:30–12:00 |
Large Scale Proteomic Profiling to Uncover Biomarkers for Heart Disease;
Peter Liu; University of Toronto, Canada |
| 12:00-13:00 |
LUNCH. Lunch provided in the Beacon Ballroom, level 3, Hyatt Hotel |
|
|
| 13:00-15:00 |
CLINICAL DAY PARALLEL SESSIONS |
| 13:00-15:00 |
INVITED WORKSHOP: NIH CLINICAL PROTEOMICS WORKSHOP
Co-Chairs: Pothur Srinivas and Robert E. Gerszten
Ballroom A, level 2, Convention Center |
Sun Oral D
13:00-13:20 |
Antibody Microarray Analysis of the Human Platelet Signaling Proteome:
Evidence for Gender Specificity; Harvey B. Pollard1; Ofer Eidelman1; Catherine
Jozwik1; Greg Mueller1; Stephen Rothwell1; Pamela L. Zeitlin2; William B.
Guggino2; David M. Jacobowitz3; Meera Srivastava1; 1Uniformed Services
University of the Health Scienc, Bethesda, MD; 2Johns Hopkins University,
Baltimore, MD; 3National Institutes of Health, Bethesda, MD ....................................1036 |
Sun Oral D
13:20-13:40 |
A Novel Approach for the Depletion of High Abundance Proteins from
Human Plasma; Amit Kapur; Alamgir Khan; Wai-Kei Shum; Sock-Hwee Tan;
Mark P Molloy; Veronika Polaskova; Mark S Baker; Australian Proteome
Analysis Facility Ltd, Sydney, NSW, Australia ...............................................................813 |
Sun Oral D
13:40-14:00 |
Novel Markers of Myocardial Ischemia; Robert E. Gerszten; Massachusetts
General Hospital, Boston, MA......................................................................................1246 |
Sun Oral D
14:00-14:20 |
An Extensive Heart Tissue Bank for Proteome Research; Cristobal G. dos
Remedios12; 1University of Sydney Bosch Institute, Sydney, Australia; 2University
of Sydney Bosch Institute, Sydney, Australia ................................................................1190 |
Sun Oral D
14:20-14:40 |
A Multi-Level Depletion Strategy Enabling the Identification of Sialyated
Glycoproteins in Plasma; Christina I. Orazine; Marina Hincapie;
William S. Hancock; Barnett Institute, Boston, MA.....................................................1045 |
Sun Oral D
14:40-15:00 |
Abundances Based on Comparative Analysis of the Human and Mouse
Plasma Proteomes; Rajasree Menon1; Thomas W Blackwell1; Kenneth E Hung2;
Bryan Krastins2; David A Sarracino2; Gilbert S Omenn1; David J States1;
1University of Michigan, Ann Arbor, MI; 2Harvard Medical School-Partners
Healthcare Center, Boston, MA....................................................................................1114 |
|
|
| 13:00-15:00 |
INVITED SYMPOSIUM: BIOINFORMATIC ANALYSES TO GAIN INSIGHTS INTO
BIOMARKERS, DISEASE AND THERAPY
Co-Chairs: Gilbert S. Omenn and Rolf Apweiler
Ballroom B, level 2, Convention Center |
Sun Oral E
13:00-13:30 |
Annotation of Proteins for Biomedical Applications; Rolf Apweiler;
EMBL-EBI, Hinxton, UK..............................................................................................1290 |
Sun Oral E
13:30-14:00 |
Critical Issues for Bioinformatics in the HUPO Plasma Proteome Project
(HPPP); Gilbert S. Omenn; University of Michigan, Ann Arbor, MI ..........................1425 |
Sun Oral E
14:00-14:30 |
Novel strategies for Glycomics Biomarker Research; Hisashi Narimatsu;
Akihiko Kameyama; Jun Hirabayashi; Research Center for Glycoscience, AIST,
Tsukuba, Japan.............................................................................................................1207 |
Sun Oral E
14:30-15:00 |
Informing the Design and Analysis of Biomarker Discovery Projects from
Lessons Learned in Biomarker Validation Studies; Martin McIntosh;
Molecular Diagnostic Program, FHCRC, Seattle, WA ................................................1422 |
|
|
| 15:30-18: 30 |
HUPO INITIATIVE MEETINGS AND WORKSHOPS (Open to all Congress registrants) |
| 15:30-18:30 |
HUPO ANTIBODY INITIATIVE WORKSHOP
Co-Chairs: Matthias Uhlen and Michael Snyder
Room 201, level 2, Convention Center |
| Recent years have witnessed a significant demand for antibodies and other affinity reagents, both for resource tools
and therapeutics. This workshop will discuss recent advances in the production of antibodies and related reagents,
and large scale projects devoted to this effort and the challenge of producing reagents to cover the entire human
proteome. New applications and measures for antibody characterization and community standards will also be
discussed. |
| 15:30-15:35 |
Introduction; Michael Snyder |
| 15:35-15:40 |
The Human Protein Atlas Program; Mathias Uhlen, Sweden |
| 15:40-15:45 |
The Sanger Atlas Program; John McCafferty, UK |
| 15:45-15:50 |
The Argonne Program; Kevin White, US |
| 15:50-15:55 |
The Los Alamos Program; Andrew Bradbury, US |
| 15:55-16:00 |
The EU ProteomeBinder Program; Mike Taussig, UK |
| 16:00-16:05 |
The EU Antibody Standards Workshop; David Sherman, France |
| 16:05-16:10 |
An Antibody Resource Pilot Database; Erik Bjorling, Sweden |
| 16:10-16:15 |
Antibodies to Cancer Proteins; Greg Downing, NCI |
| 16:15-16:30 |
BREAK. Refreshments are on Level 2 |
| 16:30-18:30 |
Panel Discussion: 1) Goals; 2) Standards, 3) Applications; 4) Paired Antibodies for
Technical Feasibility Studies; 4) Cost and Accessibility; 5) Timelines |
|
|
| 15:30-18:30 |
HUPO HGPI HUMAN DISEASE GLYCOMICS/PROTEOME INITIATIVE WORKSHOP
Co-Chairs: Naoyuki Taniguchi, Hisashi Narimatsu, and James Paulson
Room 202, level 2, Convention Center |
| 15:30-16:00 |
Recent Reports on HGPI Activity and Importance of Glycomics and Biomarkers in
Diseases; Naoyuki Taniguchi |
| 16:00-16:20 |
Results of HGPI multi-institutional pilot studies on N-glycan analyses;
Catherine Costello |
| 16:20-16:40 |
NEDO Projects Five Years: Glycogene, Structural Glycomics, and Medical
Glycoproteomics Projects; Hisashi Narimatsu |
| 16:40-17:00 |
Bioinformatics Approach to Functional Glycomics; James Paulson |
| 17:00-17:15 |
BREAK. Refreshments are on Level 2 |
| 17:15-17:35 |
A System for Intelligent Identification of Glycans Using Multi-Stage Tandem Mass
Spectrometry; Akihiro Kameyama |
| 17:35-17:55 |
Development of Lectin Microarray for Glycan Profiling and Bio-Marker
Investigation; Jun Hirabayashi |
| 17:55-18:15 |
Different Strategies for Glycopeptide Enrichment in Glycomics; Peter Roepstorff |
| 18:15-18:30 |
Summary and Closing Remarks; Hisashi Narimatsu |
|
|
| 15:30-18:30 |
HUPO HBPP INITIATIVE WORKSHOP: NEW PROTEOMICS APPROACHES FOR
FURTHER HUPO BPP STUDIES
Co-Chairs: Young Mok Park and Helmut Meyer
Room 203, level 2, Convention Center |
In this session, HUPO BPP colleagues will present and discuss new approaches and animal models for
neurodegenerative diseases. A critical evaluation of techniques and strategies in proteomics is highly appreciated. |
| 15:30-15:40 |
Welcome; Helmut E. Meyer; Bochum, Germany; and Young Mok Park; KBSI, Korea |
| 15:40-16:00 |
Protein Scape and Beyond; Herbet Thiele; Bruker Daltonics, Germany |
| 16:00-16:20 |
Novel Method for the Analysis of 2D Gels Improving Objectivity, Detection
Sensitivity and Specificity; Howard B. Gutstein; Houston, TX |
| 16:20-16:40 |
Approaches for 2D Electrophoretic Separations; Helen Kim; Birmingham, AL |
| 16:40-17:00 |
New Rodent Models for Neurodegeneration |
| 17:00-17:10 |
BREAK |
| 17:10-17:30 |
Novel Multidimensional Protein Separation Platform for Neuroproteomic Studies;
Andre K. Ottens; Gainesville, FL |
| 17:30-17:50 |
CSF Proteomics; Jing Zhang; Seattle, WA |
| 17:50-18:10 |
EU Project: Proteomics Data Collection (ProDAC); Chirstian Stephan; Bochum,
Germany |
| 18:10-18:30 |
Final Remarks |
|
|
| 15:30-18:30 |
INVITED WORKSHOP: SYSTEMS BIOLOGY AND BIOMARKER DISCOVERY
Co-Chairs: Ian Humphrey-Smith and Albert Heck
Ballroom A, level 2, Convention Center |
| 15:30-16:00 |
Post-Genomic Systems Integration as an Opportunity to Build Better Drugs &
Deliver Validated Biomarkers; Ian Humphrey-Smith |
| 16:00-16:30 |
Biomarker Discovery and Heart Failure; Albert Heck |
| 16:30-17:00 |
Myocardial Ischemia and Biomarker Analyses; Jenny Van Eyk |
| 17:00-17:30 |
Metabolic Markers as Biomarkers for Cardiovascular Diseases; Manuel Mayr |
| 17:30-18:30 |
Panel Discussion |
|
|
| 15:30-18:30 |
HUPO BIOMARKER INITIATIVE WORKSHOP
Chair: Samir Hanash
Room: 104 A, Lobby level, Convention Center |
| 15:30-16:00 |
A Road Map for Biomarker Discovery; Samir Hanash |
| 16:00-16:30 |
Computational Tools for Data Processing for Biomarker Discovery;
Martin McIntosh and Ron Beavis |
| 16:30-17:00 |
Building Bridges between Glycomics and Proteomics for Biomarker Initiatives;
Bill Hancock |
| 17:00-18:30 |
Panel Discussion: Disease Biomarker Initiative Updates from World Leaders of
Biomarker Studies at the HUPO Meeting |
|
|
| 15:30-18:30 |
HUPO HPPP INITIATIVE WORKSHOP
Co-Chairs: Young-Ki Paik and Gilbert S. Omenn
Room: 104 B, Lobby level, Convention Center |
| 15:30-16:00 |
Introduction and Overall Plan for the Next Phase of the HPPP--the Four
Components below; Gilbert S. Omenn and Young-Ki Paik |
| 16:00-16:30 |
Deep Analysis of the Plasma Proteome, for Identification, PTMs, and Quantitation
with Normal Plasma and Plasma from Patients Participating in Disease Biomarker
or Organ-Proteome Studies; Ruedi Aebersold, David Speicher, Bill Hancock,
Xiaohong Qian |
| 16:30-17:00 |
Informatics Challenges and Insights for the HPPP; Alexey Nesvizhskii, David States,
Henning Hermjakob, Eric Deutsch, Eugene Kapp |
| 17:00-17:30 |
Consensus Working Group for Standardized Protocols and Operating Procedures
with Plasma Specimens; Ruth Vanbogelen, Philip Andrews, Bruce Haywood/Craig
Gelfand, Frank Vitzthum, Dan Chan, Alex Rai, Richard Simpson |
| 17:30-18:00 |
Operating Procedures with Plasma Specimens: Ruth Vanbogelen, Philip Andrews,
Bruce Haywood/Craig Gelfand, Frank Vitzthum, Dan Chan, Alex Rai, Richard Simpson |
| 18:00-17:30 |
Working Group on HPPP Priorities for HUPO Antibody Production Initiative;
Brian Haab, Helmut E. Meyer, Sam Hanash, Rong Wang, Akhilesh Pandey, Mathias
Uhlen/representative (simultaneous workshop) |
| 18:00-18:30 |
Panel Discussion |
|
|
| 15:30-18:30 |
HUPO HLPP INITIATIVE WORKSHOP
Co-Chairs: Laura Beretta and Fuchu He
Room: 104 C, Lobby level, Convention Center |
| The HUPO Liver Proteome Project is now reaching the end of its pilot phase. During this period, the scientific
objectives have been to characterize the proteome of the healthy human liver (expression profiling, cellular
localization, post-translational modifications, protein-protein interactions) and to develop tools for its study (sample
banking, ORFeome, antibodies). Achievements will be presented during this workshop and we will discuss how to
use the information and tools generated by this international effort, to understand, diagnose and treat liver diseases. |
| 15:30-15:40 |
Introduction; Laura Beretta (US) |
| 15:40-16:00 |
Technologies + Expression Profiling; Xiaohong Qian (PRC) |
| 16:00-16:20 |
Bioinformatics; Yunping Zhu (PRC) |
| 16:20-16:40 |
Expression Profiling; Laura Beretta (US) |
| 16:40-17:00 |
Protein-Protein Interactions; ORFeome; Pengyuan Yang (PRC) |
| 17:00-17:20 |
Antibody Bank; Qi-Hong Sun (PRC) |
| 17:20-17:40 |
Liver Proteomics of Fatty Liver Disease; José Mato (Spain) |
| 17:40-18:00 |
Mouse Models; John Bergeron (Canada) |
| 18:00-18:30 |
Discussion |
